Masataka Tsuge Selected Research

Hepatitis B

1/2023	Hepatitis B Virus (HBV) Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL.
1/2022	Serum miR-192-5p levels predict the efficacy of pegylated interferon therapy for chronic hepatitis B.
12/2021	The association between hepatocarcinogenesis and intracellular alterations due to hepatitis B virus infection.
1/2021	Serum PreS1 and HBsAg ratio reflects liver fibrosis and predicts the development of hepatocellular carcinoma in chronic hepatitis B patients.
1/2021	Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection-Pilot study.
12/2018	Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes.
2/2018	Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy.
3/2017	The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients.
1/2017	The prognosis of hepatitis B inactive carriers in Japan: a multicenter prospective study.
1/2017	Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice.

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Masataka Tsuge Research Topics

Disease

59	Infections 01/2023 - 03/2005
56	Hepatocellular Carcinoma (Hepatoma) 03/2024 - 10/2005
38	Chronic Hepatitis C 01/2021 - 05/2009
22	Chronic Hepatitis B 03/2023 - 11/2006
21	Liver Cirrhosis (Hepatic Cirrhosis) 03/2024 - 09/2010
19	Neoplasms (Cancer) 11/2023 - 10/2005
17	Fibrosis (Cirrhosis) 03/2024 - 09/2010
17	Hepatitis B 01/2023 - 08/2004
12	Hepatitis C 09/2020 - 05/2009
9	Liver Diseases (Liver Disease) 01/2023 - 09/2010
7	Hepatic Encephalopathy 09/2023 - 07/2013
7	Non-alcoholic Fatty Liver Disease 04/2023 - 03/2014
6	Neoplasm Metastasis (Metastasis) 11/2023 - 06/2015
6	Thrombosis (Thrombus) 04/2021 - 06/2015
6	Disease Progression 04/2020 - 12/2007
5	Type 2 Diabetes Mellitus (MODY) 01/2023 - 03/2014
5	Hepatitis 01/2021 - 02/2012
5	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 05/2017 - 07/2010
4	Acute Liver Failure (Fulminant Hepatic Failure) 09/2023 - 08/2014
3	Virus Diseases (Viral Diseases) 03/2024 - 03/2015
3	Inflammation (Inflammations) 01/2023 - 09/2010
3	Insulin Resistance 03/2022 - 12/2014
3	Carcinogenesis 01/2021 - 10/2005
3	Chronic Hepatitis (Chronic Active Hepatitis) 01/2020 - 03/2017
3	Anemia 06/2017 - 06/2011
2	Portal Hypertension 03/2024 - 11/2020
2	Fatigue 11/2023 - 11/2014
2	Acute-On-Chronic Liver Failure 10/2023 - 10/2023
2	Weight Loss (Weight Reduction) 01/2023 - 03/2016
2	Glucose Intolerance 03/2022 - 02/2017
2	Hypoglycemia (Reactive Hypoglycemia) 03/2022 - 02/2017
2	Liver Failure 02/2021 - 06/2008
2	Necrosis 01/2021 - 01/2018

Drug/Important Bio-Agent (IBA)

48	InterferonsIBA 01/2022 - 05/2007
25	Ribavirin (Virazole)FDA LinkGeneric 01/2020 - 01/2010
23	Antiviral Agents (Antivirals)IBA 01/2023 - 09/2013
14	lenvatinibIBA 11/2023 - 01/2019
14	daclatasvirIBA 01/2020 - 01/2014
13	Sorafenib (BAY 43-9006)FDA Link 09/2023 - 06/2015
13	asunaprevirIBA 01/2020 - 06/2016
11	Hepatitis B Surface Antigens (HBsAg)FDA Link 03/2023 - 12/2015
11	AntigensIBA 01/2022 - 02/2012
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2006
10	RNA (Ribonucleic Acid)IBA 12/2021 - 06/2008
9	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 03/2005
7	Alanine Transaminase (SGPT)IBA 01/2023 - 06/2009
6	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2018
6	Bevacizumab (Avastin)FDA Link 03/2024 - 01/2023
6	atezolizumabIBA 03/2024 - 01/2023
6	CytokinesIBA 09/2023 - 09/2010
6	NucleotidesIBA 01/2023 - 10/2013
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2023 - 07/2012
6	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 03/2014
6	NucleosidesIBA 01/2019 - 05/2007
6	telaprevirIBA 06/2016 - 09/2011
5	Hemoglobins (Hemoglobin)IBA 01/2023 - 06/2011
5	SofosbuvirIBA 11/2020 - 04/2017
5	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 05/2017 - 07/2010
5	Lamivudine (Epivir)FDA Link 08/2010 - 11/2005
4	nasIBA 03/2024 - 02/2012
4	alpha-Fetoproteins (alpha-Fetoprotein)IBA 02/2024 - 05/2016
4	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2012
4	EnzymesIBA 02/2021 - 06/2008
4	regorafenibIBA 01/2021 - 09/2018
4	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 10/2015
4	Protease Inhibitors (Protease Inhibitor)IBA 04/2020 - 07/2010
4	SimeprevirIBA 03/2017 - 06/2016
3	Interleukin-6 (Interleukin 6)IBA 10/2023 - 01/2014
3	Prothrombin (Factor II)IBA 09/2023 - 12/2017
3	Blood Glucose (Blood Sugar)IBA 01/2023 - 01/2018
3	Small Interfering RNA (siRNA)IBA 01/2022 - 02/2006
3	Tyrosine Kinase InhibitorsIBA 01/2021 - 01/2020
3	Immunoglobulin G (IgG)IBA 01/2021 - 06/2008
3	Viral AntigensIBA 10/2020 - 02/2012
3	ChemokinesIBA 07/2019 - 01/2011
3	entecavir FDA Link 12/2018 - 12/2007
3	ledipasvirIBA 12/2018 - 04/2017
3	Hepatitis B e AntigensIBA 01/2018 - 10/2013
3	Complementary DNA (cDNA)IBA 05/2017 - 01/2011
2	Alkaline PhosphataseIBA 03/2024 - 10/2019
2	Zoledronic Acid (Zometa)FDA Link 11/2023 - 03/2015
2	Interleukin-8 (Interleukin 8)IBA 09/2023 - 12/2018
2	VaccinesIBA 03/2023 - 11/2016
2	LipidsIBA 01/2023 - 11/2017
2	Therapeutic UsesIBA 01/2023 - 07/2021
2	LuciferasesIBA 01/2022 - 12/2021
2	Circulating Tumor DNAIBA 06/2021 - 09/2015
2	Immune Checkpoint InhibitorsIBA 02/2021 - 10/2020
2	glecaprevir and pibrentasvirIBA 01/2021 - 01/2020
2	HLA-DQB1 antigen (HLA DQB1)IBA 12/2020 - 01/2013
2	Fetal Proteins (Fetoprotein)IBA 11/2020 - 01/2018
2	Histone MethyltransferasesIBA 11/2020 - 10/2005
2	pembrolizumabIBA 10/2020 - 07/2020

Therapy/Procedure

81	Therapeutics 03/2024 - 05/2009
14	Liver Transplantation 09/2023 - 12/2010
11	Drug Therapy (Chemotherapy) 04/2021 - 04/2015
4	Surgical Portasystemic Shunt (Portosystemic Shunt) 08/2019 - 07/2013
3	Radiotherapy 04/2021 - 01/2018
2	Aftercare (After-Treatment) 10/2023 - 10/2016
2	Glycemic Control 03/2022 - 03/2014